diff --git a/src/duckstation-qt/memorycardeditordialog.cpp b/src/duckstation-qt/memorycardeditordialog.cpp
index 731de6288..be2676ee4 100644
--- a/src/duckstation-qt/memorycardeditordialog.cpp
+++ b/src/duckstation-qt/memorycardeditordialog.cpp
@@ -33,7 +33,7 @@ MemoryCardEditorDialog::~MemoryCardEditorDialog() = default;
 
 bool MemoryCardEditorDialog::setCardA(const QString& path)
 {
-  const int index = m_ui.cardAPath->findData(QVariant(path));
+  const int index = m_ui.cardAPath->findData(QVariant(QDir::toNativeSeparators(path)));
   if (index < 0)
     return false;
 
@@ -43,7 +43,7 @@ bool MemoryCardEditorDialog::setCardA(const QString& path)
 
 bool MemoryCardEditorDialog::setCardB(const QString& path)
 {
-  const int index = m_ui.cardBPath->findData(QVariant(path));
+  const int index = m_ui.cardBPath->findData(QVariant(QDir::toNativeSeparators(path)));
   if (index < 0)
     return false;
 
@@ -114,7 +114,8 @@ void MemoryCardEditorDialog::loadCardFromComboBox(Card* card, int index)
   QString filename;
   if (index == 1)
   {
-    filename = QFileDialog::getOpenFileName(this, tr("Select Memory Card"), QString(), tr(MEMORY_CARD_IMAGE_FILTER));
+    filename = QDir::toNativeSeparators(
+      QFileDialog::getOpenFileName(this, tr("Select Memory Card"), QString(), tr(MEMORY_CARD_IMAGE_FILTER)));
     if (!filename.isEmpty())
     {
       // add to combo box
@@ -238,8 +239,8 @@ void MemoryCardEditorDialog::newCard(Card* card)
 {
   promptForSave(card);
 
-  QString filename =
-    QFileDialog::getSaveFileName(this, tr("Select Memory Card"), QString(), tr(MEMORY_CARD_IMAGE_FILTER));
+  QString filename = QDir::toNativeSeparators(
+    QFileDialog::getSaveFileName(this, tr("Select Memory Card"), QString(), tr(MEMORY_CARD_IMAGE_FILTER)));
   if (filename.isEmpty())
     return;
 
@@ -264,8 +265,8 @@ void MemoryCardEditorDialog::openCard(Card* card)
 {
   promptForSave(card);
 
-  QString filename =
-    QFileDialog::getOpenFileName(this, tr("Select Memory Card"), QString(), tr(MEMORY_CARD_IMAGE_FILTER));
+  QString filename = QDir::toNativeSeparators(
+    QFileDialog::getOpenFileName(this, tr("Select Memory Card"), QString(), tr(MEMORY_CARD_IMAGE_FILTER)));
   if (filename.isEmpty())
     return;
 
diff --git a/src/duckstation-qt/memorycardsettingswidget.cpp b/src/duckstation-qt/memorycardsettingswidget.cpp
index 6df775b40..8ab9140a2 100644
--- a/src/duckstation-qt/memorycardsettingswidget.cpp
+++ b/src/duckstation-qt/memorycardsettingswidget.cpp
@@ -11,7 +11,8 @@
 #include <QtWidgets/QFileDialog>
 #include <QtWidgets/QLabel>
 
-static constexpr char MEMORY_CARD_IMAGE_FILTER[] = QT_TRANSLATE_NOOP("MemoryCardSettingsWidget", "All Memory Card Types (*.mcd *.mcr *.mc)");
+static constexpr char MEMORY_CARD_IMAGE_FILTER[] =
+  QT_TRANSLATE_NOOP("MemoryCardSettingsWidget", "All Memory Card Types (*.mcd *.mcr *.mc)");
 
 MemoryCardSettingsWidget::MemoryCardSettingsWidget(QtHostInterface* host_interface, QWidget* parent,
                                                    SettingsDialog* dialog)
@@ -104,8 +105,8 @@ void MemoryCardSettingsWidget::createPortSettingsUi(SettingsDialog* dialog, int
 
 void MemoryCardSettingsWidget::onBrowseMemoryCardPathClicked(int index)
 {
-  QString path =
-    QFileDialog::getOpenFileName(this, tr("Select path to memory card image"), QString(), tr(MEMORY_CARD_IMAGE_FILTER));
+  QString path = QDir::toNativeSeparators(QFileDialog::getOpenFileName(this, tr("Select path to memory card image"),
+                                                                       QString(), tr(MEMORY_CARD_IMAGE_FILTER)));
   if (path.isEmpty())
     return;